Hairy Cell Leukemia (HCL) and Hairy Cell Leukemia Variant (HCL-V)

نویسندگان

  • Vasantha Brito-Babapulle
  • Estella Matutes
  • Daniel Catovsky
چکیده

Cells from hairy cell leukemia (HCL) and hairy cell leukemia variant (HCL-V) have a distinct immunophenotype which is of a mature but not terminally differentiated activated B-cell. Although some similarities exist between these two conditions like the expression of B-cell activation marker CD103, CD11c and IgG heavy chain expression, differences exists between these two diseases. HCL is positive for CD25 (anti IL2 receptor) and HC2 while HCL-V is negative for CD25 and HC2.

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تاریخ انتشار 2011